Human_Genes_Functions
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GRCh38.p14 + GENCODE Release 50local-onlyPDO SQLite primaryread-only query modesqlite3 fallback available

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TP53

Query: TP53 Type: All 20 on this page 61 total Page 3 / 4 PDO SQLite primary
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Gene match type: fts

AFG1L

AFG1 like ATPase
ENSG00000135537 matched: TP53
Symbol
AFG1L
Gene name
AFG1 like ATPase
Ensembl Gene ID
ENSG00000135537
NCBI Gene ID
246269
Match type
fts
Matched value
TP53

…Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to…, Gene symbol: AFG1L Gene name: AFG1 like ATPase Chromosome: 6 Gene type: protein_coding Gene status: Coordinates: 6:108294892-108526796 + Aliases: alias_symbol:AFG1; alias_name:ATPase family gene 1 homolog (S. cerevisiae)…

Open gene detail Gene result
Gene match type: fts

PRMT6

protein arginine methyltransferase 6
ENSG00000198890 matched: TP53
Symbol
PRMT6
Gene name
protein arginine methyltransferase 6
Ensembl Gene ID
ENSG00000198890
NCBI Gene ID
55170
Match type
fts
Matched value
TP53

…Repression of TP53 blocks cellular senescence (By similarity). Also methylates histone…, Gene symbol: PRMT6 Gene name: protein arginine methyltransferase 6 Chromosome: 1 Gene type: protein_coding Gene status: Coordinates: 1:107056674-107067636 + Aliases: alias_symbol:FLJ10559; previous_symbol:HRMT1L6; previo…

Open gene detail Gene result
Gene match type: fts

COPS7B

COP9 signalosome subunit 7B
ENSG00000144524 matched: TP53
Symbol
COPS7B
Gene name
COP9 signalosome subunit 7B
Ensembl Gene ID
ENSG00000144524
NCBI Gene ID
64708
Match type
fts
Matched value
TP53

…CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the…, Gene symbol: COPS7B Gene name: COP9 signalosome subunit 7B Chromosome: 2 Gene type: protein_coding Gene status: Coordinates: 2:231781660-231809254 + Aliases: alias_symbol:CSN7B; previous_name:COP9 (constitutive photomorp…

Open gene detail Gene result
Gene match type: fts

COPS7A

COP9 signalosome subunit 7A
ENSG00000111652 matched: TP53
Symbol
COPS7A
Gene name
COP9 signalosome subunit 7A
Ensembl Gene ID
ENSG00000111652
NCBI Gene ID
50813
Match type
fts
Matched value
TP53

…CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the…, Gene symbol: COPS7A Gene name: COP9 signalosome subunit 7A Chromosome: 12 Gene type: protein_coding Gene status: Coordinates: 12:6724014-6732462 + Aliases: alias_symbol:CSN7A; previous_name:COP9 (constitutive photomorpho…

Open gene detail Gene result
Gene match type: fts

GNL3L

G protein nucleolar 3 like
ENSG00000130119 matched: TP53
Symbol
GNL3L
Gene name
G protein nucleolar 3 like
Ensembl Gene ID
ENSG00000130119
NCBI Gene ID
54552
Match type
fts
Matched value
TP53

…By acting on MDM2, may affect TP53 activity. Required for normal processing…, Gene symbol: GNL3L Gene name: G protein nucleolar 3 like Chromosome: X Gene type: protein_coding Gene status: Coordinates: X:54529900-54621565 + Aliases: alias_symbol:FLJ10613; alias_symbol:GNL3B; alias_name:G protein nu…

Open gene detail Gene result
Gene match type: fts

PDCD5

programmed cell death 5
ENSG00000105185 matched: TP53
Symbol
PDCD5
Gene name
programmed cell death 5
Ensembl Gene ID
ENSG00000105185
NCBI Gene ID
9141
Match type
fts
Matched value
TP53

…to prevent MDM2-mediated degradation of TP53 and promote TP53-mediated signaling (PubMed:19616514, PubMed:22914926…, Gene symbol: PDCD5 Gene name: programmed cell death 5 Chromosome: 19 Gene type: protein_coding Gene status: Coordinates: 19:32581062-32587453 + Aliases: alias_symbol:TFAR19; alias_symbol:MGC9294; alias_name:TFAR19 novel …

Open gene detail Gene result
Gene match type: fts

COPS9

COP9 signalosome subunit 9
ENSG00000172428 matched: TP53
Symbol
COPS9
Gene name
COP9 signalosome subunit 9
Ensembl Gene ID
ENSG00000172428
NCBI Gene ID
150678
Match type
fts
Matched value
TP53

…CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the…, Gene symbol: COPS9 Gene name: COP9 signalosome subunit 9 Chromosome: 2 Gene type: protein_coding Gene status: Coordinates: 2:240126563-240136807 - Aliases: alias_symbol:CSNAP; alias_name:CSN acidic protein; previous_symb…

Open gene detail Gene result
Gene match type: fts

PPP1R13L

protein phosphatase 1 regulatory subunit 13 like
ENSG00000104881 matched: TP53
Symbol
PPP1R13L
Gene name
protein phosphatase 1 regulatory subunit 13 like
Ensembl Gene ID
ENSG00000104881
NCBI Gene ID
10848
Match type
fts
Matched value
TP53

…evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455…, Gene symbol: PPP1R13L Gene name: protein phosphatase 1 regulatory subunit 13 like Chromosome: 19 Gene type: protein_coding Gene status: Coordinates: 19:45379634-45406367 - Aliases: alias_symbol:RAI; alias_symbol:IASPP; a…

Open gene detail Gene result
Gene match type: fts

NUPR1

nuclear protein 1, transcriptional regulator
ENSG00000176046 matched: TP53
Symbol
NUPR1
Gene name
nuclear protein 1, transcriptional regulator
Ensembl Gene ID
ENSG00000176046
NCBI Gene ID
26471
Match type
fts
Matched value
TP53

…through the complex formation with TP53 and EP300 that binds CDKN1A promoter…, Gene symbol: NUPR1 Gene name: nuclear protein 1, transcriptional regulator Chromosome: 16 Gene type: protein_coding Gene status: Coordinates: 16:28532708-28539068 - Aliases: alias_symbol:COM1; alias_symbol:p8; alias_name…

Open gene detail Gene result
Gene match type: fts

COPS2

COP9 signalosome subunit 2
ENSG00000166200 matched: TP53
Symbol
COPS2
Gene name
COP9 signalosome subunit 2
Ensembl Gene ID
ENSG00000166200
NCBI Gene ID
9318
Match type
fts
Matched value
TP53

…CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the…, Gene symbol: COPS2 Gene name: COP9 signalosome subunit 2 Chromosome: 15 Gene type: protein_coding Gene status: Coordinates: 15:49106068-49155661 - Aliases: alias_symbol:TRIP15; alias_symbol:ALIEN; alias_symbol:CSN2; prev…

Open gene detail Gene result
Gene match type: fts

ING1

inhibitor of growth family member 1
ENSG00000153487 matched: TP53
Symbol
ING1
Gene name
inhibitor of growth family member 1
Ensembl Gene ID
ENSG00000153487
NCBI Gene ID
3621
Match type
fts
Matched value
TP53

…with the tumor suppressor protein TP53 and is a component of the…, Gene symbol: ING1 Gene name: inhibitor of growth family member 1 Chromosome: 13 Gene type: protein_coding Gene status: Coordinates: 13:110712736-110748944 + Aliases: alias_symbol:p33ING1; alias_symbol:p33ING1b; alias_sym…

Open gene detail Gene result
Gene match type: fts

IFI16

interferon gamma inducible protein 16
ENSG00000163565 matched: TP53
Symbol
IFI16
Gene name
interferon gamma inducible protein 16
Ensembl Gene ID
ENSG00000163565
NCBI Gene ID
3428
Match type
fts
Matched value
TP53

…May be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA…, Gene symbol: IFI16 Gene name: interferon gamma inducible protein 16 Chromosome: 1 Gene type: protein_coding Gene status: Coordinates: 1:158999938-159055156 + Aliases: alias_symbol:IFNGIP1; alias_symbol:PYHIN2; ccds_id:CC…

Open gene detail Gene result
Gene match type: fts

COPS8

COP9 signalosome subunit 8
ENSG00000198612 matched: TP53
Symbol
COPS8
Gene name
COP9 signalosome subunit 8
Ensembl Gene ID
ENSG00000198612
NCBI Gene ID
10920
Match type
fts
Matched value
TP53

…CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the…, Gene symbol: COPS8 Gene name: COP9 signalosome subunit 8 Chromosome: 2 Gene type: protein_coding Gene status: Coordinates: 2:237085877-237103208 + Aliases: alias_symbol:COP9; alias_symbol:CSN8; alias_symbol:MGC1297; alia…

Open gene detail Gene result
Gene match type: fts

GPS1

G protein pathway suppressor 1
ENSG00000169727 matched: TP53
Symbol
GPS1
Gene name
G protein pathway suppressor 1
Ensembl Gene ID
ENSG00000169727
NCBI Gene ID
2873
Match type
fts
Matched value
TP53

…CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the…, Gene symbol: GPS1 Gene name: G protein pathway suppressor 1 Chromosome: 17 Gene type: protein_coding Gene status: Coordinates: 17:82050691-82058063 + Aliases: alias_symbol:COPS1; alias_symbol:CSN1; alias_name:COP9 signal…

Open gene detail Gene result
Gene match type: fts

COPS4

COP9 signalosome subunit 4
ENSG00000138663 matched: TP53
Symbol
COPS4
Gene name
COP9 signalosome subunit 4
Ensembl Gene ID
ENSG00000138663
NCBI Gene ID
51138
Match type
fts
Matched value
TP53

…CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the…, Gene symbol: COPS4 Gene name: COP9 signalosome subunit 4 Chromosome: 4 Gene type: protein_coding Gene status: Coordinates: 4:83034447-83075818 + Aliases: alias_symbol:CSN4; alias_symbol:SGN4; previous_name:COP9 (constitu…

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Gene match type: fts

RPL23A

ribosomal protein L23a
ENSG00000198242 matched: TP53
Symbol
RPL23A
Gene name
ribosomal protein L23a
Ensembl Gene ID
ENSG00000198242
NCBI Gene ID
6147
Match type
fts
Matched value
TP53

…May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination…, Gene symbol: RPL23A Gene name: ribosomal protein L23a Chromosome: 17 Gene type: protein_coding Gene status: Coordinates: 17:28719940-28724365 + Aliases: alias_symbol:L23A; alias_symbol:uL23; ccds_id:CCDS11241; refseq_acc…

Open gene detail Gene result
Gene match type: fts

BANP

BTG3 associated nuclear protein
ENSG00000172530 matched: TP53
Symbol
BANP
Gene name
BTG3 associated nuclear protein
Ensembl Gene ID
ENSG00000172530
NCBI Gene ID
54971
Match type
fts
Matched value
TP53

…Promotes TP53 activation, which causes cell cycle arrest (By similarity). Plays…, Gene symbol: BANP Gene name: BTG3 associated nuclear protein Chromosome: 16 Gene type: protein_coding Gene status: Coordinates: 16:87949127-88083442 + Aliases: alias_symbol:SMARBP1; alias_symbol:SMAR1; alias_symbol:FLJ20…

Open gene detail Gene result
Gene match type: fts

KLF15

KLF transcription factor 15
ENSG00000163884 matched: TP53
Symbol
KLF15
Gene name
KLF transcription factor 15
Ensembl Gene ID
ENSG00000163884
NCBI Gene ID
28999
Match type
fts
Matched value
TP53

…Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression…, Gene symbol: KLF15 Gene name: KLF transcription factor 15 Chromosome: 3 Gene type: protein_coding Gene status: Coordinates: 3:126342635-126357462 - Aliases: alias_symbol:KKLF; alias_name:kidney-enriched Kruppel-like fact…

Open gene detail Gene result
Gene match type: fts

COPS6

COP9 signalosome subunit 6
ENSG00000168090 matched: TP53
Symbol
COPS6
Gene name
COP9 signalosome subunit 6
Ensembl Gene ID
ENSG00000168090
NCBI Gene ID
10980
Match type
fts
Matched value
TP53

…CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the…, Gene symbol: COPS6 Gene name: COP9 signalosome subunit 6 Chromosome: 7 Gene type: protein_coding Gene status: Coordinates: 7:100088948-100095185 + Aliases: alias_symbol:MOV34-34KD; alias_symbol:CSN6; alias_name:COP9 subu…

Open gene detail Gene result
Gene match type: fts

USP3

ubiquitin specific peptidase 3
ENSG00000140455 matched: TP53
Symbol
USP3
Gene name
ubiquitin specific peptidase 3
Ensembl Gene ID
ENSG00000140455
NCBI Gene ID
9960
Match type
fts
Matched value
TP53

…Acts as a positive regulator of TP53 by deubiquitinating and stabilizing it…, Gene symbol: USP3 Gene name: ubiquitin specific peptidase 3 Chromosome: 15 Gene type: protein_coding Gene status: Coordinates: 15:63504501-63594640 + Aliases: previous_name:ubiquitin specific protease 3; ccds_id:CCDS3226…

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