Prototype stage

Gene detail

Read-only gene view with summary, GO, UniProt, NCBI, and representative sequence links.

GRCh38.p14 + GENCODE Release 50local-onlyPDO SQLite primaryread-only query modesqlite3 fallback available

Gene detail

BANP

BANP

protein_coding 16 87,949,127 - 88,083,442 PDO SQLite primary read-only query mode

Overview Summary GO UniProt Representative Transcripts FASTA ClinVar disease associations

Overview

Gene ID
ENSG00000172530

Gene type
protein_coding

Chromosome
16

Coordinates
87,949,127 - 88,083,442

Strand
+

Status
not available

NCBI summary UniProt GO Transcript FASTA Protein FASTA

Aliases

54971 BEN domain containing 1 BEND1 CCDS10966 CCDS42215 CCDS54052 CCDS54053 CCDS54054 CCDS54055 CCDS92203 CCDS92204 DKFZp761H172 ENST00000682872.1 FLJ10177 FLJ20538 NM_001386991.1 NM_017869 Q8N9N5 SMAR1 SMARBP1

Summary

GENCODE gene_type=protein_coding; HGNC symbol=BANP; HGNC name=BTG3 associated nuclear protein; alias_count=20; RefSeq=NM_017869; UniProt=Q8N9N5; MANE Select=ENST00000682872.1,NM_001386991.1

Source: GENCODE + HGNC complete set

54971 • protein-coding

This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

NCBI Gene

UniProt

Q8N9N5 • reviewed

Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function (By similarity). Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity). Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels (PubMed:16166625). Promotes TP53 activation, which causes cell cycle arrest (By similarity). Plays a role in the regulation of alternative splicing (PubMed:26080397). Binds to CD44 pre-mRNA and negatively regulates the inclusion of CD44 proximal variable exons v2-v6 but has no effect on distal variable exons v7-v10 (PubMed:26080397)

Protein BANP · Nucleus; Nucleus speckle; Cytoplasm

Q8N9N5 • reviewed

Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function (By similarity). Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity). Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels (PubMed:16166625). Promotes TP53 activation, which causes cell cycle arrest (By similarity). Plays a role in the regulation of alternative splicing (PubMed:26080397). Binds to CD44 pre-mRNA and negatively regulates the inclusion of CD44 proximal variable exons v2-v6 but has no effect on distal variable exons v7-v10 (PubMed:26080397)

Protein BANP · Nucleus; Nucleus speckle; Cytoplasm

Q8N9N5 • reviewed

Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function (By similarity). Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity). Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels (PubMed:16166625). Promotes TP53 activation, which causes cell cycle arrest (By similarity). Plays a role in the regulation of alternative splicing (PubMed:26080397). Binds to CD44 pre-mRNA and negatively regulates the inclusion of CD44 proximal variable exons v2-v6 but has no effect on distal variable exons v7-v10 (PubMed:26080397)

Protein BANP · Nucleus; Nucleus speckle; Cytoplasm

Q8N9N5 • reviewed

Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function (By similarity). Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity). Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels (PubMed:16166625). Promotes TP53 activation, which causes cell cycle arrest (By similarity). Plays a role in the regulation of alternative splicing (PubMed:26080397). Binds to CD44 pre-mRNA and negatively regulates the inclusion of CD44 proximal variable exons v2-v6 but has no effect on distal variable exons v7-v10 (PubMed:26080397)

Protein BANP · Nucleus; Nucleus speckle; Cytoplasm

Q8N9N5 • reviewed

Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function (By similarity). Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity). Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels (PubMed:16166625). Promotes TP53 activation, which causes cell cycle arrest (By similarity). Plays a role in the regulation of alternative splicing (PubMed:26080397). Binds to CD44 pre-mRNA and negatively regulates the inclusion of CD44 proximal variable exons v2-v6 but has no effect on distal variable exons v7-v10 (PubMed:26080397)

Protein BANP · Nucleus; Nucleus speckle; Cytoplasm

Q8N9N5 • reviewed

Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function (By similarity). Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity). Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels (PubMed:16166625). Promotes TP53 activation, which causes cell cycle arrest (By similarity). Plays a role in the regulation of alternative splicing (PubMed:26080397). Binds to CD44 pre-mRNA and negatively regulates the inclusion of CD44 proximal variable exons v2-v6 but has no effect on distal variable exons v7-v10 (PubMed:26080397)

Protein BANP · Nucleus; Nucleus speckle; Cytoplasm

Q8N9N5 • reviewed

Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function (By similarity). Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity). Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels (PubMed:16166625). Promotes TP53 activation, which causes cell cycle arrest (By similarity). Plays a role in the regulation of alternative splicing (PubMed:26080397). Binds to CD44 pre-mRNA and negatively regulates the inclusion of CD44 proximal variable exons v2-v6 but has no effect on distal variable exons v7-v10 (PubMed:26080397)

Protein BANP · Nucleus; Nucleus speckle; Cytoplasm

GO annotations

Cellular component

GO:0005737 cytoplasm (IEA)
GO:0016604 nuclear body (IDA)
GO:0016607 nuclear speck (IEA)
GO:0005654 nucleoplasm (IDA)
GO:0005654 nucleoplasm (TAS)
GO:0005634 nucleus (IEA)
GO:0005634 nucleus (EXP)

Molecular function

GO:0003677 DNA binding (IEA)
GO:0042802 identical protein binding (IPI)
GO:0042802 identical protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)

+ 183 more

Representative

Representative transcript
ENST00000355022

Representative protein
ENSP00000347125.4

Representative type
CCDS

Candidate count
43

GENCODE Release 50 annotation GTF · transcript.tag=CCDS; transcript_support_level=1

Transcript FASTA Protein FASTA

Transcripts

Transcript ID	Name	Type	Status	Protein	Location
ENST00000854712	BANP-230	protein_coding	not available	ENSP00000524771.1	16:87,949,127 - 88,077,320 +
ENST00000854713	BANP-231	protein_coding	not available	ENSP00000524772.1	16:87,949,127 - 88,077,320 +
ENST00000854714	BANP-232	protein_coding	not available	ENSP00000524773.1	16:87,949,127 - 88,077,318 +
ENST00000854715	BANP-233	protein_coding	not available	ENSP00000524774.1	16:87,949,127 - 88,077,320 +
ENST00000854716	BANP-234	protein_coding	not available	ENSP00000524775.1	16:87,949,127 - 88,077,317 +
ENST00000854717	BANP-235	protein_coding	not available	ENSP00000524776.1	16:87,949,127 - 88,077,317 +
ENST00000854718	BANP-236	protein_coding	not available	ENSP00000524777.1	16:87,949,127 - 88,077,317 +
ENST00000854719	BANP-237	protein_coding	not available	ENSP00000524778.1	16:87,949,127 - 88,077,316 +
ENST00000854720	BANP-238	protein_coding	not available	ENSP00000524779.1	16:87,949,127 - 88,077,317 +
ENST00000854721	BANP-239	protein_coding	not available	ENSP00000524780.1	16:87,949,127 - 88,077,021 +
ENST00000854722	BANP-240	protein_coding	not available	ENSP00000524781.1	16:87,949,127 - 88,077,021 +
ENST00000854723	BANP-241	protein_coding	not available	ENSP00000524782.1	16:87,949,127 - 88,076,993 +
ENST00000854724	BANP-242	protein_coding	not available	ENSP00000524783.1	16:87,949,127 - 88,076,993 +
ENST00000854726	BANP-243	protein_coding	not available	ENSP00000524785.1	16:87,949,127 - 88,076,993 +
ENST00000854727	BANP-244	protein_coding	not available	ENSP00000524786.1	16:87,949,127 - 88,076,993 +
ENST00000854728	BANP-245	protein_coding	not available	ENSP00000524787.1	16:87,949,127 - 88,076,993 +
ENST00000981663	BANP-292	nonsense_mediated_decay	not available	ENSP00000651480.1	16:87,949,221 - 88,076,993 +
ENST00000981662	BANP-291	nonsense_mediated_decay	not available	ENSP00000651479.1	16:87,949,238 - 88,077,315 +
ENST00000981664	BANP-293	nonsense_mediated_decay	not available	ENSP00000651481.1	16:87,949,242 - 88,076,993 +
ENST00000569400	BANP-225	protein_coding_CDS_not_defined	not available	not available	16:87,949,244 - 87,984,251 +

FASTA

FASTA output is generated by backend query; the raw FASTA path is not exposed.

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ClinVar disease associations

ClinVar disease associations: 0

ClinVar gene-disease tables are missing. Build the candidate database first.