Human_Genes_Functions
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GRCh38.p14 + GENCODE Release 50local-onlyPDO SQLite primaryread-only query modesqlite3 fallback available

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TP53

Query: TP53 Type: All 20 on this page 41 total Page 2 / 3 PDO SQLite primary
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Gene match type: fts

TIGAR

TP53 induced glycolysis regulatory phosphatase
ENSG00000078237 matched: TP53
Symbol
TIGAR
Gene name
TP53 induced glycolysis regulatory phosphatase
Ensembl Gene ID
ENSG00000078237
NCBI Gene ID
57103
Match type
fts
Matched value
TP53

…GENCODE gene_type=protein_coding; HGNC symbol=TIGAR; HGNC name=TP53 induced glycolysis regulatory…, Gene symbol: TIGAR Gene name: TP53 induced glycolysis regulatory phosphatase Chromosome: 12 Gene type: protein_coding Gene status: Coordinates: 12:4307763-4360028 + Aliases: alias_name:TP53-induced glycolysis and apoptos…

Open gene detail Gene result
Gene match type: fts

HIPK4

homeodomain interacting protein kinase 4
ENSG00000160396 matched: TP53
Symbol
HIPK4
Gene name
homeodomain interacting protein kinase 4
Ensembl Gene ID
ENSG00000160396
NCBI Gene ID
147746
Match type
fts
Matched value
TP53

…Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53…, Gene symbol: HIPK4 Gene name: homeodomain interacting protein kinase 4 Chromosome: 19 Gene type: protein_coding Gene status: Coordinates: 19:40379271-40390181 - Aliases: alias_symbol:FLJ32818; ccds_id:CCDS12555; refseq_a…

Open gene detail Gene result
Gene match type: fts

PPP1R13B

protein phosphatase 1 regulatory subunit 13B
ENSG00000088808 matched: TP53
Symbol
PPP1R13B
Gene name
protein phosphatase 1 regulatory subunit 13B
Ensembl Gene ID
ENSG00000088808
NCBI Gene ID
23368
Match type
fts
Matched value
TP53

…Regulates TP53 by enhancing the DNA binding and transactivation function of TP53…, Gene symbol: PPP1R13B Gene name: protein phosphatase 1 regulatory subunit 13B Chromosome: 14 Gene type: protein_coding Gene status: Coordinates: 14:103733177-103847616 - Aliases: alias_symbol:p53BP2-like; alias_symbol:KI…

Open gene detail Gene result
Gene match type: fts

PBK

PDZ binding kinase
ENSG00000168078 matched: TP53
Symbol
PBK
Gene name
PDZ binding kinase
Ensembl Gene ID
ENSG00000168078
NCBI Gene ID
55872
Match type
fts
Matched value
TP53

…When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and…, Gene symbol: PBK Gene name: PDZ binding kinase Chromosome: 8 Gene type: protein_coding Gene status: Coordinates: 8:27809532-27838082 - Aliases: alias_symbol:TOPK; alias_symbol:FLJ14385; alias_symbol:Nori-3; alias_symbol:…

Open gene detail Gene result
Gene match type: fts

UBXN2A

UBX domain protein 2A
ENSG00000173960 matched: TP53
Symbol
UBXN2A
Gene name
UBX domain protein 2A
Ensembl Gene ID
ENSG00000173960
NCBI Gene ID
165324
Match type
fts
Matched value
TP53

…Plays a role in the inhibition of STUB1-mediated TP53 degradation, via its…, Gene symbol: UBXN2A Gene name: UBX domain protein 2A Chromosome: 2 Gene type: protein_coding Gene status: Coordinates: 2:23926788-24004909 + Aliases: previous_symbol:UBXD4; previous_name:UBX domain containing 4; ccds_id:…

Open gene detail Gene result
Gene match type: fts

GTPBP4

GTP binding protein 4
ENSG00000107937 matched: TP53
Symbol
GTPBP4
Gene name
GTP binding protein 4
Ensembl Gene ID
ENSG00000107937
NCBI Gene ID
23560
Match type
fts
Matched value
TP53

…Acts as a TP53 repressor, preventing TP53 stabilization and cell cycle arrest…, Gene symbol: GTPBP4 Gene name: GTP binding protein 4 Chromosome: 10 Gene type: protein_coding Gene status: Coordinates: 10:988409-1020001 + Aliases: alias_symbol:CRFG; alias_symbol:NGB; alias_symbol:FLJ10690; alias_symbo…

Open gene detail Gene result
Gene match type: fts

TRIM69

tripartite motif containing 69
ENSG00000185880 matched: TP53
Symbol
TRIM69
Gene name
tripartite motif containing 69
Ensembl Gene ID
ENSG00000185880
NCBI Gene ID
140691
Match type
fts
Matched value
TP53

…Also plays a role in cataract formation together with TP53 (PubMed:30844644).…, Gene symbol: TRIM69 Gene name: tripartite motif containing 69 Chromosome: 15 Gene type: protein_coding Gene status: Coordinates: 15:44728986-44767829 + Aliases: alias_symbol:Trif; alias_symbol:TRIMLESS; previous_symbol:R…

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Gene match type: fts

DDX24

DEAD-box helicase 24
ENSG00000089737 matched: TP53
Symbol
DDX24
Gene name
DEAD-box helicase 24
Ensembl Gene ID
ENSG00000089737
NCBI Gene ID
57062
Match type
fts
Matched value
TP53

…Plays an inhibitory role in TP53 transcriptional activity and subsequently in TP53…, Gene symbol: DDX24 Gene name: DEAD-box helicase 24 Chromosome: 14 Gene type: protein_coding Gene status: Coordinates: 14:94048287-94081216 - Aliases: previous_name:DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 24; previou…

Open gene detail Gene result
Gene match type: fts

MORC3

MORC family CW-type zinc finger 3
ENSG00000159256 matched: TP53
Symbol
MORC3
Gene name
MORC family CW-type zinc finger 3
Ensembl Gene ID
ENSG00000159256
NCBI Gene ID
23515
Match type
fts
Matched value
TP53

…Sumoylated MORC3-NBs associates with PML-NBs and recruits TP53 and SP100, thus regulating…, Gene symbol: MORC3 Gene name: MORC family CW-type zinc finger 3 Chromosome: 21 Gene type: protein_coding Gene status: Coordinates: 21:36320180-36386148 + Aliases: alias_symbol:ZCW5; alias_symbol:NXP2; alias_symbol:KIAA01…

Open gene detail Gene result
Gene match type: fts

MUL1

mitochondrial E3 ubiquitin protein ligase 1
ENSG00000090432 matched: TP53
Symbol
MUL1
Gene name
mitochondrial E3 ubiquitin protein ligase 1
Ensembl Gene ID
ENSG00000090432
NCBI Gene ID
79594
Match type
fts
Matched value
TP53

…Mediates polyubiquitination of cytoplasmic TP53 at 'Lys-24' which targets TP53 for proteasomal…, Gene symbol: MUL1 Gene name: mitochondrial E3 ubiquitin protein ligase 1 Chromosome: 1 Gene type: protein_coding Gene status: Coordinates: 1:20495722-20508163 - Aliases: alias_symbol:FLJ12875; alias_symbol:MULAN; alias_s…

Open gene detail Gene result
Gene match type: fts

DAZAP2

DAZ associated protein 2
ENSG00000183283 matched: TP53
Symbol
DAZAP2
Gene name
DAZ associated protein 2
Ensembl Gene ID
ENSG00000183283
NCBI Gene ID
9802
Match type
fts
Matched value
TP53

…This limits the expression of a number of cell death-mediating TP53 target…, Gene symbol: DAZAP2 Gene name: DAZ associated protein 2 Chromosome: 12 Gene type: protein_coding Gene status: Coordinates: 12:51238724-51272164 + Aliases: alias_symbol:KIAA0058; ccds_id:CCDS44884; ccds_id:CCDS44885; ccds…

Open gene detail Gene result
Gene match type: fts

RYBP

RING1 and YY1 binding protein
ENSG00000163602 matched: TP53
Symbol
RYBP
Gene name
RING1 and YY1 binding protein
Ensembl Gene ID
ENSG00000163602
NCBI Gene ID
23429
Match type
fts
Matched value
TP53

…Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role…, Gene symbol: RYBP Gene name: RING1 and YY1 binding protein Chromosome: 3 Gene type: protein_coding Gene status: Coordinates: 3:72371825-72446621 - Aliases: alias_symbol:YEAF1; alias_symbol:AAP1; alias_symbol:DEDAF; alias…

Open gene detail Gene result
Gene match type: fts

PTGES

prostaglandin E synthase
ENSG00000148344 matched: TP53
Symbol
PTGES
Gene name
prostaglandin E synthase
Ensembl Gene ID
ENSG00000148344
NCBI Gene ID
9536
Match type
fts
Matched value
TP53

…Its expression can also be induced by tumor suppressor protein TP53, and…, Gene symbol: PTGES Gene name: prostaglandin E synthase Chromosome: 9 Gene type: protein_coding Gene status: Coordinates: 9:129738331-129753078 - Aliases: alias_symbol:mPGES-1; alias_symbol:MGST-IV; alias_symbol:PIG12; al…

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Gene match type: fts

FBXO22

F-box protein 22
ENSG00000167196 matched: TP53
Symbol
FBXO22
Gene name
F-box protein 22
Ensembl Gene ID
ENSG00000167196
NCBI Gene ID
26263
Match type
fts
Matched value
TP53

…In complex with KDM4A, also regulates the abundance of TP53 by targeting…, Gene symbol: FBXO22 Gene name: F-box protein 22 Chromosome: 15 Gene type: protein_coding Gene status: Coordinates: 15:75903853-75942511 + Aliases: alias_symbol:FBX22; alias_symbol:FISTC1; alias_name:FIST domain containin…

Open gene detail Gene result
Gene match type: fts

MDM4

MDM4 regulator of p53
ENSG00000198625 matched: TP53
Symbol
MDM4
Gene name
MDM4 regulator of p53
Ensembl Gene ID
ENSG00000198625
NCBI Gene ID
4194
Match type
fts
Matched value
TP53

…Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation…, Gene symbol: MDM4 Gene name: MDM4 regulator of p53 Chromosome: 1 Gene type: protein_coding Gene status: Coordinates: 1:204516369-204558120 + Aliases: alias_symbol:MDMX; alias_symbol:HDMX; previous_name:mouse double minut…

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Gene match type: fts

BRD7

bromodomain containing 7
ENSG00000166164 matched: TP53
Symbol
BRD7
Gene name
bromodomain containing 7
Ensembl Gene ID
ENSG00000166164
NCBI Gene ID
29117
Match type
fts
Matched value
TP53

…Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of…, Gene symbol: BRD7 Gene name: bromodomain containing 7 Chromosome: 16 Gene type: protein_coding Gene status: Coordinates: 16:50313487-50369059 - Aliases: alias_symbol:CELTIX1; alias_symbol:BP75; alias_symbol:SMARCI1; prev…

Open gene detail Gene result
Gene match type: fts

MUC1

mucin 1, cell surface associated
ENSG00000185499 matched: TP53
Symbol
MUC1
Gene name
mucin 1, cell surface associated
Ensembl Gene ID
ENSG00000185499
NCBI Gene ID
4582
Match type
fts
Matched value
TP53

…Binds, together with KLF4, the PE21 promoter element of TP53 and represses…, Gene symbol: MUC1 Gene name: mucin 1, cell surface associated Chromosome: 1 Gene type: protein_coding Gene status: Coordinates: 1:155185824-155192916 - Aliases: alias_symbol:CD227; alias_symbol:PEM; alias_symbol:ADMCKD; …

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Gene match type: fts

DAXX

death domain associated protein
ENSG00000204209 matched: TP53
Symbol
DAXX
Gene name
death domain associated protein
Ensembl Gene ID
ENSG00000204209
NCBI Gene ID
1616
Match type
fts
Matched value
TP53

…activity of MDM2 towards TP53, thereby promoting TP53 ubiquitination and subsequent proteasomal…, Gene symbol: DAXX Gene name: death domain associated protein Chromosome: 6 Gene type: protein_coding Gene status: Coordinates: 6:33318558-33323259 - Aliases: alias_symbol:DAP6; previous_name:death-associated protein 6; c…

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Gene match type: fts

TRIM24

tripartite motif containing 24
ENSG00000122779 matched: TP53
Symbol
TRIM24
Gene name
tripartite motif containing 24
Ensembl Gene ID
ENSG00000122779
NCBI Gene ID
8805
Match type
fts
Matched value
TP53

…After sufficient DNA repair has occurred, TP53 activates TRIM24 transcription, ultimately leading…, Gene symbol: TRIM24 Gene name: tripartite motif containing 24 Chromosome: 7 Gene type: protein_coding Gene status: Coordinates: 7:138460193-138590023 + Aliases: alias_symbol:hTIF1; alias_symbol:Tif1a; alias_symbol:RNF82;…

Open gene detail Gene result
Gene match type: fts

ZMAT3

zinc finger matrin-type 3
ENSG00000172667 matched: TP53
Symbol
ZMAT3
Gene name
zinc finger matrin-type 3
Ensembl Gene ID
ENSG00000172667
NCBI Gene ID
64393
Match type
fts
Matched value
TP53

…May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation…, Gene symbol: ZMAT3 Gene name: zinc finger matrin-type 3 Chromosome: 3 Gene type: protein_coding Gene status: Coordinates: 3:178958103-179072323 - Aliases: alias_symbol:WIG1; alias_symbol:MGC10613; alias_symbol:FLJ12296; …

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