Human_Genes_Functions
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Prototype stage

Gene detail

Read-only gene view with summary, GO, UniProt, NCBI, and representative sequence links.

GRCh38.p14 + GENCODE Release 50local-onlyPDO SQLite primaryread-only query modesqlite3 fallback available

Gene detail

ZMAT3

ZMAT3

protein_coding 3 178,958,103 - 179,072,323 PDO SQLite primary read-only query mode
Overview Summary GO UniProt Representative Transcripts FASTA ClinVar disease associations

Overview

Gene ID
ENSG00000172667
Gene type
protein_coding
Chromosome
3
Coordinates
178,958,103 - 179,072,323
Strand
-
Status
not available
NCBI summary UniProt GO Transcript FASTA Protein FASTA

Aliases

64393 CCDS3224 CCDS46962 ENST00000311417.7 FLJ12296 MGC10613 NM_022470.4 NM_152240 PAG608 Q9HA38 WIG-1 WIG1

Summary

GENCODE gene_type=protein_coding; HGNC symbol=ZMAT3; HGNC name=zinc finger matrin-type 3; alias_count=12; RefSeq=NM_152240; UniProt=Q9HA38; MANE Select=ENST00000311417.7,NM_022470.4

Source: GENCODE + HGNC complete set

64393 • protein-coding

This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. [provided by RefSeq, Jul 2008]

NCBI Gene

UniProt

Q9HA38 • reviewed

Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus

Zinc finger matrin-type protein 3 · Nucleus; Nucleus, nucleolus

Q9HA38 • reviewed

Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus

Zinc finger matrin-type protein 3 · Nucleus; Nucleus, nucleolus

GO annotations

Cellular component
  • GO:0005730 nucleolus (IEA)
  • GO:0005654 nucleoplasm (IDA)
  • GO:0005634 nucleus (IEA)
  • GO:0005634 nucleus (EXP)
Molecular function
  • GO:0003723 RNA binding (HDA)
  • GO:0003676 nucleic acid binding (IEA)
  • GO:0005515 protein binding (IPI)
  • GO:0005515 protein binding (IPI)
  • GO:0005515 protein binding (IPI)
  • GO:0005515 protein binding (IPI)
  • GO:0005515 protein binding (IPI)
  • GO:0005515 protein binding (IPI)
  • GO:0005515 protein binding (IPI)
  • GO:0008270 zinc ion binding (IEA)

Representative

Representative transcript
ENST00000311417
Representative protein
ENSP00000311221.2
Representative type
CCDS
Candidate count
7

GENCODE Release 50 annotation GTF · transcript.tag=CCDS; transcript_support_level=1

Transcript FASTA Protein FASTA

Transcripts

Transcript ID Name Type Status Protein Location
ENST00000652290 ZMAT3-204 protein_coding not available ENSP00000498847.1 3:178,958,103 - 179,072,323 -
ENST00001116476 ZMAT3-214 protein_coding not available ENSP00000786281.1 3:179,002,619 - 179,072,323 -
ENST00000311417 ZMAT3-201 protein_coding not available ENSP00000311221.2 3:179,017,223 - 179,071,809 -
ENST00001144612 ZMAT3-215 protein_coding not available ENSP00000806182.1 3:179,017,223 - 179,072,323 -
ENST00000867369 ZMAT3-205 protein_coding not available ENSP00000537428.1 3:179,023,711 - 179,072,323 -
ENST00000867370 ZMAT3-206 protein_coding not available ENSP00000537429.1 3:179,023,711 - 179,072,323 -
ENST00000867371 ZMAT3-207 protein_coding not available ENSP00000537430.1 3:179,023,711 - 179,072,323 -
ENST00000867372 ZMAT3-208 protein_coding not available ENSP00000537431.1 3:179,023,711 - 179,072,323 -
ENST00000992683 ZMAT3-211 nonsense_mediated_decay not available ENSP00000662500.1 3:179,023,711 - 179,071,817 -
ENST00000992684 ZMAT3-212 nonsense_mediated_decay not available ENSP00000662501.1 3:179,023,711 - 179,071,805 -
ENST00001080681 ZMAT3-213 nonsense_mediated_decay not available ENSP00000750487.1 3:179,023,711 - 179,071,866 -
ENST00000931263 ZMAT3-210 protein_coding not available ENSP00000601322.1 3:179,023,716 - 179,071,592 -
ENST00000432729 ZMAT3-203 protein_coding not available ENSP00000396506.1 3:179,023,739 - 179,072,323 -
ENST00000867373 ZMAT3-209 protein_coding not available ENSP00000537432.1 3:179,023,739 - 179,071,592 -
ENST00000414084 ZMAT3-202 protein_coding not available ENSP00000398920.1 3:179,027,757 - 179,071,566 -

FASTA

FASTA output is generated by backend query; the raw FASTA path is not exposed.

Open transcript export Open protein export

ClinVar disease associations

ClinVar disease associations: 0

ClinVar gene-disease tables are missing. Build the candidate database first.