Prototype stage

Gene detail

Read-only gene view with summary, GO, UniProt, NCBI, and representative sequence links.

GRCh38.p14 + GENCODE Release 50local-onlyPDO SQLite primaryread-only query modesqlite3 fallback available

Gene detail

RPRM

protein_coding 2 153,477,338 - 153,478,762 PDO SQLite primary read-only query mode

Overview Summary GO UniProt Representative Transcripts FASTA ClinVar disease associations

Overview

Gene ID
ENSG00000177519

Gene type
protein_coding

Chromosome
2

Coordinates
153,477,338 - 153,478,762

Strand
-

Status
not available

NCBI summary UniProt GO Transcript FASTA Protein FASTA

Aliases

56475 CCDS2198 ENST00000325926.4 FLJ90327 NM_019845 NM_019845.3 Q9NS64 REPRIMO REPRIMO candidate mediator of the p53 dependent G2 arrest reprimo, TP53 dependant G2 arrest mediator candidate reprimo, TP53 dependent G2 arrest mediator candidate

Summary

GENCODE gene_type=protein_coding; HGNC symbol=RPRM; HGNC name=reprimo; alias_count=12; RefSeq=NM_019845; UniProt=Q9NS64; MANE Select=ENST00000325926.4,NM_019845.3

Source: GENCODE + HGNC complete set

56475 • protein-coding

Alliance of Genome Resources Predicted to be involved in regulation of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle. Predicted to be located in membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

NCBI Gene

UniProt

Q9NS64 • reviewed

May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDK1 activity and nuclear translocation of the CDC2 cyclin B1 complex (By similarity)

Protein reprimo · Cytoplasm; Membrane

GO annotations

Biological process

GO:0051726 regulation of cell cycle (TAS)
GO:0007346 regulation of mitotic cell cycle (IBA)

Cellular component

GO:0005737 cytoplasm (IEA)
GO:0005737 cytoplasm (IEA)
GO:0005737 cytoplasm (TAS)
GO:0005737 cytoplasm (IBA)
GO:0016020 membrane (IEA)

Molecular function

GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)

+ 68 more

Representative

Representative transcript
ENST00000325926

Representative protein
ENSP00000314946.3

Representative type
CCDS

Candidate count
1

GENCODE Release 50 annotation GTF · transcript.tag=CCDS; transcript_support_level=NA

Transcript FASTA Protein FASTA

Transcripts

Transcript ID	Name	Type	Status	Protein	Location
ENST00000325926	RPRM-201	protein_coding	not available	ENSP00000314946.3	2:153,477,338 - 153,478,762 -

FASTA

FASTA output is generated by backend query; the raw FASTA path is not exposed.

Open transcript export Open protein export

ClinVar disease associations

ClinVar disease associations: 0

ClinVar gene-disease tables are missing. Build the candidate database first.