Prototype stage

Gene detail

Read-only gene view with summary, GO, UniProt, NCBI, and representative sequence links.

GRCh38.p14 + GENCODE Release 50local-onlyPDO SQLite primaryread-only query modesqlite3 fallback available

Gene detail

FANCG

protein_coding 9 35,073,793 - 35,082,444 PDO SQLite primary read-only query mode

Overview Summary GO UniProt Representative Transcripts FASTA ClinVar disease associations

Overview

Gene ID
ENSG00000221829

Gene type
protein_coding

Chromosome
9

Coordinates
35,073,793 - 35,082,444

Strand
-

Status
not available

NCBI summary UniProt GO Transcript FASTA Protein FASTA

Aliases

2189 CCDS6574 DNA repair protein XRCC9 ENST00000378643.8 FAG Fanconi anemia complementation group G NM_004629 NM_004629.2 O15287 X-ray repair complementing defective repair in Chinese hamster cells 9 X-ray repair, complementing defective, in Chinese hamster, 9 XRCC9

Summary

GENCODE gene_type=protein_coding; HGNC symbol=FANCG; HGNC name=FA complementation group G; alias_count=15; RefSeq=NM_004629; UniProt=O15287; MANE Select=ENST00000378643.8,NM_004629.2

Source: GENCODE + HGNC complete set

2189 • protein-coding

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G. [provided by RefSeq, Jul 2008]

NCBI Gene

UniProt

O15287 • reviewed

DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene

Fanconi anemia group G protein · Nucleus; Cytoplasm

O15287 • reviewed

Fanconi anemia group G protein · Nucleus; Cytoplasm

GO annotations

Biological process

GO:0006974 DNA damage response (IEA)
GO:0006974 DNA damage response (IBA)
GO:0006281 DNA repair (TAS)
GO:0036297 interstrand cross-link repair (IEA)
GO:0036297 interstrand cross-link repair (NAS)
GO:0007005 mitochondrion organization (IMP)

Cellular component

GO:0043240 Fanconi anaemia nuclear complex (IEA)
GO:0043240 Fanconi anaemia nuclear complex (IDA)
GO:0043240 Fanconi anaemia nuclear complex (IDA)
GO:0043240 Fanconi anaemia nuclear complex (IDA)
GO:0043240 Fanconi anaemia nuclear complex (NAS)
GO:0043240 Fanconi anaemia nuclear complex (IDA)
GO:0043240 Fanconi anaemia nuclear complex (IBA)
GO:0000785 chromatin (IDA)
GO:0005737 cytoplasm (IEA)
GO:0005829 cytosol (TAS)

+ 13 more

Molecular function

GO:0003684 damaged DNA binding (TAS)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)
GO:0005515 protein binding (IPI)

+ 35 more

Representative

Representative transcript
ENST00000378643

Representative protein
ENSP00000367910.4

Representative type
CCDS

Candidate count
3

GENCODE Release 50 annotation GTF · transcript.tag=CCDS; transcript_support_level=1

Transcript FASTA Protein FASTA

Transcripts

Transcript ID	Name	Type	Status	Protein	Location
ENST00001028145	FANCG-241	nonsense_mediated_decay	not available	ENSP00000697962.1	9:35,073,793 - 35,079,755 -
ENST00000448890	FANCG-203	protein_coding	not available	ENSP00000409607.2	9:35,073,820 - 35,079,942 -
ENST00000696710	FANCG-217	protein_coding	not available	ENSP00000512826.1	9:35,073,820 - 35,082,444 -
ENST00000881804	FANCG-223	protein_coding	not available	ENSP00000551863.1	9:35,073,820 - 35,082,444 -
ENST00000881805	FANCG-224	protein_coding	not available	ENSP00000551864.1	9:35,073,820 - 35,082,444 -
ENST00000881806	FANCG-225	protein_coding	not available	ENSP00000551865.1	9:35,073,820 - 35,082,444 -
ENST00000881807	FANCG-226	protein_coding	not available	ENSP00000551866.1	9:35,073,820 - 35,082,444 -
ENST00000938586	FANCG-227	protein_coding	not available	ENSP00000608645.1	9:35,073,820 - 35,082,444 -
ENST00000960438	FANCG-228	protein_coding	not available	ENSP00000630497.1	9:35,073,820 - 35,082,444 -
ENST00000960439	FANCG-229	protein_coding	not available	ENSP00000630498.1	9:35,073,820 - 35,082,444 -
ENST00000960440	FANCG-230	protein_coding	not available	ENSP00000630499.1	9:35,073,820 - 35,082,444 -
ENST00000960442	FANCG-232	protein_coding	not available	ENSP00000630501.1	9:35,073,820 - 35,082,444 -
ENST00000960443	FANCG-233	protein_coding	not available	ENSP00000630502.1	9:35,073,820 - 35,082,444 -
ENST00001028141	FANCG-237	protein_coding	not available	ENSP00000697958.1	9:35,073,820 - 35,082,444 -
ENST00001028144	FANCG-240	protein_coding	not available	ENSP00000697961.1	9:35,073,820 - 35,082,444 -
ENST00001072360	FANCG-247	protein_coding	not available	ENSP00000742166.1	9:35,073,820 - 35,082,444 -
ENST00001072361	FANCG-248	protein_coding	not available	ENSP00000742167.1	9:35,073,820 - 35,082,444 -
ENST00001140467	FANCG-250	protein_coding	not available	ENSP00000810920.1	9:35,073,820 - 35,082,444 -
ENST00001072358	FANCG-245	nonsense_mediated_decay	not available	ENSP00000742164.1	9:35,073,821 - 35,080,024 -
ENST00001028140	FANCG-236	nonsense_mediated_decay	not available	ENSP00000697957.1	9:35,073,827 - 35,080,000 -

FASTA

FASTA output is generated by backend query; the raw FASTA path is not exposed.

Open transcript export Open protein export

ClinVar disease associations

ClinVar disease associations: 0

ClinVar gene-disease tables are missing. Build the candidate database first.