Human_Genes_Functions
Local prototype • PDO SQLite primary • read-only query mode • sqlite3 fallback available

Prototype stage

Human_Genes_Functions

Search human genes and Mondo diseases in a local read-only prototype.

GRCh38.p14 + GENCODE Release 50local-onlyPDO SQLite primaryread-only query modesqlite3 fallback available

Local knowledge platform

Human gene knowledge, staged for a larger UI.

This prototype is the first thin Web layer over the existing local database. It keeps the SQLite file, FASTA assets, scripts, and manifests behind the backend, while the browser sees a modern read-only search and detail experience.

GRCh38.p14 + GENCODE Release 50 PDO SQLite primary read-only query mode sqlite3 fallback available
Examples: TP53, MT-ND1, XIST, DNA repair
No CDN, no login, no write operations
Sensitive assets stay behind the backend

Primary action

Search

Quick entry points

Example queries

TP53 Li-Fraumeni syndrome MONDO:0018875 DNA repair

Coverage

What this prototype shows

  • Gene symbol and identifier lookup
  • Alias-aware search and FTS keyword search
  • Gene detail pages with GO, UniProt, and NCBI summary sections
  • Safe FASTA output routed through backend logic

Safety boundary

Safety boundary

  • SQLite and FASTA files stay behind the backend
  • Prototype code lives only in the local workspace
  • No Apache change, no public deployment
  • Future UI/API split can reuse the same service layer